Lift the motherboard straight up and remove it.

Before securing the motherboard during reassembly:

Move all cables that connect to the motherboard (display, keyboard, speaker, and antenna) out of the way so they don't get stuck under the motherboard when it's reinserted.

Make sure the alignment pins on the frame are in their cutouts on the motherboard.

Push down on right edge of the motherboard to ensure the USB-C and thunderbolt ports are in their recesses.