What drives are supported?

As for using it with your MacBook Pro M4 system, use disk utility to reformat the M.2 SSD for Mac use using GUID and APFS if you intend to use it exclusively with your or other Mac systems for the best performance and reliability of the SSD it's self.

As far as performance of the case independent of the SSD you use, this case is just a USB-C interface it is not the enhanced versions of USB-C Apple has created supporting ThunderBolt-3 or the very newest ThunderBolt-4 which with the correct M.2 SSD can gain a bit more throughput!

But before you jump, think about this!

Does owning a super fast car in the middle of a dense city offer what the car can do over a simpler economy class car? Clearly not! But then again, driving in the countryside on roads designed to support speed or a race track is the better environment for this speed demon.

So look at your usage needs, most people won't need or gain benefit of the faster case and connection as well as the most high end M.2 SSD's when used in a single bay case like this. These higher end SSD's and interfaces are more beneficial to multi bay enclosures which offer RAID services to push the performance to the wall!

The only exceptions is code compiling, video rendering or building AI LLM processes which all run on the drive when being mobile.