Bottom row of keyboard is not responding

pheobe Brown if it is just the keyboard that is not responding in that area, you could try a hard reset. If nothing responds at that area, you may be looking at a bad digitizer. For the hard reset try this

Confirm the device is powered off.

Hold the Power and Home key simultaneously.

Release the Power and Home key once the NOOK logo appears. A Factory Reset prompt will appear.

To continue, press the Home key.

To exit, press the Power key.

To change the digitizer you will have to disassemble your Nook. Use these guides for that.