Possible to unplug camera and microphone(s)?

Your only hope here is tape to cover the iSight camera lens & a cut off head phone plug to kill the internal microphone!

This series uses a highly intergraded architecture to such a point there is no means to disconnect internally the camera or microphone physically.

With that said why are you worried? Unless someone has direct access to your system to RAT it, there is no means to spy on you without you knowing.

Besides you can always turn the system off or put it to sleep mode ;-}