Did you review this Question and its answer? [https://www.ifixit.com/Answers/View/172280/Can+the+TC+Drive+be+upgraded+to+5+TB|Can the TC Drive be upgraded to 5 TB?]
Many of these drives are intended for NAS units which are RAID'ed as they don't have the access speed a desktop drive have when used alone. They also run hotter, need more power and require more head room (z height) than what the TC can offer. We looked at upgrading a few for our smaller satellite offices to lessen the WAN usage. After careful review we decided not to go down that path.