I replaced the cracked screen and ported over the metal shield from the cracked screen in order to avoid any potential issues with the home button.
The hardest part was to unstick the lower connector of the home button flat cable: that glue was quite strong and the possibility of damaging the flat cable was quite realistic!
If you want to avoid a potential "error 53" in the future when updating your iPhone, you will need to get the screen metal shield from the cracked screen and replace it on the new screen. The screen metal shield has the cable that connect the home button to the motherboard.
If you just replace the cracked screen with a new assembly one ( which has its own metal shield and home button cable glued to it ) the iPhone motherboard could potentially not recognize your home button sensor and go into "brick mode" .
I replaced the hard drive following the guide and used the adhesive strips which are a must.
You DO NEED to be very careful with the step of the "credit card" used to separate the screen from the frame.
Make sure to design a reference line on the card in order to avoid to push it too far inside the frame and risk to damage the screen connections. Many users failed to perform this part of the repair procedure and had to replace the screen itself.