It looks like it is possible! You’ll want to press Graph+Enter+8. Here’s the instruction for each possible keypad:
[image|2053862]
Source: [https://hackspire.org/index.php/Operating_System#Startup_key_combinations|hackspire.org]
One important thing about the cable, the Nspire requires a Mini-USB connector which is slightly bigger than the more common Micro-USB you mentioned. :)
Note: I had help from Adriweb on this one since I’m more experienced with the TI 84 lineup rather than Nspire calculators.