Take a look into BIOS. There is an option for the touch pad (pointing device) to turn it on/off. I do not remember the exact terms, but after some years with a dead touch pad, I googled on “how to enter BIOS in ASUS XXXX , Windows 10 “. I started with downloading new drivers, so I do not know if it is necessary to do that. Anyway, for some reason, after an update in Windows 10, my touch pad was set on “off”, deactivated. Now it works again.