I have similar issues with ASUS even on desktop, where even a tiny application like "ASUS TUF DETECTIVE" could literally bog or id say bug down a "high end desktop" and ruin an entire experience. (the issue is not entirely about ASUS though, its about the apps - no matter how tiny they are - that could really eat up resources when not optimized or if malware attacks )
I suggest you do the ff to see what's really happening (if that thing still has warranty, it might be a good idea to have them check on it if nothing listed below works):
Software:
[] run on SAFE mode (see if the overall speed improves while in this mode) and uninstall unnecessary apps.
[] use a Kaspersky Rescue disk https://support.kaspersky.com/4162 (its a linux system that disinfects your windows - if due to a malware issue)
(if you are not in espionage biz or an NSA, you have nothing to worry about the recent squabble between the US gov and Kaspersky)
[] if you've set it up to auto update the OS, then try rolling back or better a '''clean install of OS ''' might be the last resort but can prove handy if nothing works (I've had tons of issues w/ WIN 10 often related to drivers etc. Also consider win7 w/c in "my opinion" is still more stable. )
Hardware (if no more warranty):
[] try removing the HDD then boot the laptop (see if anything improves).
let us know if anything improves so far.