It may work, but there's a good chance that if put more then 128GB of files on the drive, it may begin to act up. I have one of these, and it's given me a heck of a lot of trouble with hard drives. From what I've read, the IDE controller (REV. A) can be incredibly unreliable. On the other side, theres a chance that the limit is bypassed by the linux bootloader and may mask the full capacity of the drive until the operating system has begun to load, since when you install linux on a mac, it installs a GRUB-Like boot manager (Or at least it did on my mac). This may bypass the limit through the that.